a) They link the leading strand DNA polymerase and the lagging strand DNA polymerase together. SHPRH function is an important deterrent to mutagenesis and carcinogenesis in humans; The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes; Expression of this apoptosis-related protein may be a useful marker in cervix cancer development. b) The anticodon on the tRNA base pairs to the codon on the mRNA. WebA DNA polymerase extends the primed segments, forming Okazaki fragments. DNA Polymerases ???? Function Why is the DNA synthesis of the lagging strand considered discontinuous? N.p., 12 Sept. 2003. (adsbygoogle = window.adsbygoogle || []).push({}); Copyright 2010-2018 Difference Between. Okazaki fragments It has both 3 to 5 exonuclease activity and 5 to 3 polymerase activity. 3. Chunks of DNA, called Okazaki fragments, are then added to the lagging strand also in the 5 to 3 direction. The reaction that shows the working polymerase is the phosphoryl group transfer. The DNA clamp assembles on the DNA at the replication fork and "slides" along the DNA with the Given below are molecular biology mcqs for the better understanding of concepts related to molecular biology. Acide ribonuclique Wikipdia Polymerase 1 is composed of 928 amino acids. Helicase 1. The Okazaki fragments should be attached into This enzyme exists in different forms varying from shape and size. Replication begins with active 54; 70; Okazaki fragments; Satellite segments; Kornberg segment; Double-helix segment; 15. Learn the definition of DNA helicase, then explore how it gains access to DNA, its role, and its function in the human body. Pol 3 catalyzes the 5 to 3 DNA polymerization. A type of DNA polymerase, DNA polymerase I, arrives and removes the RNA primers, replacing them with DNA. Multiple functions of DNA polymerases.Critical reviews in plant sciences. Pol 2 catalyzes the fidelity and processivity of DNA replication. What characteristic of DNA allows two connected DNA polymerases to synthesize both the leading and lagging strands? U.S. National Library of Medicine, Mar. Which DNA strand is synthesized continuously? DNA polymerase 3 is the main enzyme which catalyzes the DNA synthesis, while DNA polymerase 1 and 2 are involved in DNA repairing and proofreading. What is DNA replication? YourGenome John David Jackson, Patricia Meglich, Robert Mathis, Sean Valentine, David N. Shier, Jackie L. Butler, Ricki Lewis. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA template strand using base-pairing interactions or RNA by half ladder replication.. A DNA polymerase from the b) They enable one parental DNA strand and one newly synthesized DNA strand to be held together. b) Bacteria can begin translation before transcription has terminated. DNA clamp Topoisomerase DNA polymerases in biotechnology.Frontiers. Pol 1 catalyzes the repairing of DNA damages. Polymerase 2 is composed of 783 amino acids. While the The synthesis of the lagging strand is discontinuous since the newly formed strand is disjointed. During DNA replication the synthesis of the leading strand of DNA results in fragments known as. Codon 4. 11. b) Viral species are not classified as part of any of the three domains. mRNA comprises only 13% of total RNA samples. 14. It was first discovered in E coli by Arthur Kornberg in 1955. As shown in the animation, the start codon also codes for which amino acid? DNA polymerase 1, 2 and 3 are found only in prokaryotic organisms, and they play different roles in DNA replication. Which of the following physical methods of microbial control denatures proteins as a mechanism of action? It was discovered by Thomas Kornberg in 1970. Template binding; Catalytic binding; Promoter binding; Cation binding; 2. 3. WebDrag the labels to their appropriate locations in the diagram to describe the name or function of each structure. Nuclease 1. It has a 5 to 3 exonuclease activity; thus, it is popular as a DNA repairing enzyme rather than a DNA replicating enzyme. Lehman, I. R. Discovery of DNA Polymerase.Journal of Biological Chemistry. Primase. Short strands of - primer are used in DNA replication. Helicases are often used to separate strands of a DNA double helix or a self-annealed RNA molecule using the energy from ATP hydrolysis, a process characterized by the breaking of hydrogen bonds between annealed nucleotide bases.They also function to remove nucleic acid-associated proteins and catalyze homologous DNA recombination. A codon is a sequence of three nucleotide bases/letters in a DNA or RNA strand, that is a part of the genetic code. Most such primers are excised from newly synthesized lagging strand DNA by endonucleases of the family RNase H. In eukaryotes and in archaea, the flap endonuclease FEN1 also participates in the processing of Okazaki fragments. WebStudy with Quizlet and memorize flashcards containing terms like Sort these nucleotide building blocks by their name or classification., Sort the parts of a nucleic acid according to whether they occur exclusively in DNA or RNA, or if they occur in both forms of nucleic acid., What is the abbreviation for deoxythymidine-5'-monophosphate? a) It serves as the template for DNA replication. Les cellules WebA polymerase is an enzyme (EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids. 06 Mar. Which of the factors is heat stable? Side by Side Comparison DNA Polymerase 1 vs 2 vs 3 dna replication DNA polymerase 1, 2 and 3 are prokaryotic DNA polymerases involved in DNA replication. This is the simplistic DNA RNA protein pathway published by James Watson in the first edition of The Molecular Biology of the Gene (1965). Transcription Compare the Difference Between Similar Terms. 6. 3. 7. There are different forms of DNA polymerase enzyme found in eukaryotes and prokaryotes. Degree in Plant Science, M.Sc. Leading Strand The key difference between DNA polymerase 1 2 and 3 mainly relies on the prime function of each enzyme. WebThe I-35W Mississippi River bridge (officially known as Bridge 9340) was an eight-lane, steel truss arch bridge that carried Interstate 35W across the Mississippi River one-half mile (875 m) downstream from the Saint Anthony Falls in Minneapolis, Minnesota, United States.The bridge opened in 1967 and was Minnesota's third busiest, carrying 140,000 vehicles daily. DNA replication and maintenance are mainly governed by DNA polymerases in the cell. WebOkazaki Fragments Function. This is facilitated by a special enzyme called DNA polymerase. in Molecular and Applied Microbiology, and PhD in Applied Microbiology. Polymerase I (pol I) completes chain synthesis between Okazaki fragments on the lagging strand. A) Breaks hydrogen bonds, unwinding DNA double helix. DNA polymerase 2 (Pol 2) is a prokaryotic enzyme which catalyzes the DNA replication. 5. It was first discovered from E Coli by Thomas Kornberg in 1970. The first DNA topoisomerase was discovered in bacteria by James Wang in 1971 and was initially named (omega) protein; it is now called Escherichia coli (E. coli) topoisomerase I (topo I) and is a representative of the type IA family of enzymes.Subsequently, a similar activity was found in eukaryotic cells (rat liver) by It is mainly concerned with the interrelationships between DNA, RNA and protein synthesis. Which statement regarding viral species is true? 2007. Of all polymerases, it catalyzes the highest rate of chain elongation and is the most processive. Polymerase II (pol II) is mostly involved in proofreading and DNA repair. It also has the ability to catalyze multiple polymerizations prior to releasing the template DNA, and connecting Okazaki fragments together by filling new DNA, and removing RNA primers. WebFunction. When synthesizing new DNA by DNA polymerase, it starts from the 3 end and directs the synthesis towards the 5 end by adding nucleotides at a time, complementary to the template DNA. DNA He only wants dogs with short, brown fur. Overview and Key Difference d) Two double-stranded DNA molecules, each consisting of one parental strand and one daughter strand. How does the ribosome know if the entering charged tRNA is correct? 5111 - Gene ResultPCNA proliferating cell nuclear antigen [ (human)] Infer why some single-celled eukaryotes might form a colony. The lagging strand is affected because it requires an RNA primer for each Okazaki fragment produced. Her research interests include Bio-fertilizers, Plant-Microbe Interactions, Molecular Microbiology, Soil Fungi, and Fungal Ecology. WebL'acide ribonuclique ou ARN (en anglais, RNA, pour ribonucleic acid) est un acide nuclique prsent chez pratiquement tous les tres vivants, et aussi chez certains virus.L'ARN est trs proche chimiquement de l'ADN et il est d'ailleurs en gnral synthtis dans les cellules partir d'un segment d'ADN matrice dont il est une copie. How many RNA polymerases are present in a bacterial system? During the initiation step of translation, the fMet charged tRNA assembles in which site of the ribosome? Bio test 4 This enzyme helps in the synthesis of RNA primer complementary to the DNA template strand. What would happen if the mRNA codon that coded for Cys was mutated in the third position from a U to an A? 9. The main replication enzyme particularly for the Mitochondrial DNA. All rights reserved. How many codons code for the amino acid arginine? a) Lagging strand, DNA ligase, and discontinuous. Transcription produces which of the following? WebThe function of subunit of polymerase is. The DNA clamp assembles on the DNA at the replication fork and "slides" along The DNA clamp is an + protein that assembles into a multimeric, six-domain ring structure that completely encircles the DNA double helix as the polymerase adds nucleotides to the growing strand. PolymeraseDomains By (unknown) Molecule of the Month, March 2000 Protein Data Bank (Public Domain) via Commons Wikimedia What is DNA Polymerase 3 A ubiquitous task in cells is the removal of Okazaki fragment RNA primers from replication. Which of the following processes does not occur in prokaryotes? They belong to several families: A, B, C, D, X, Y and RT. Successful c) An organism must copy its DNA to pass genetic information to its offspring. 2.Gardner, Andrew F., and Zvi Kelman. DNA clamp Central dogma of molecular biology Give a reason why the dialysing solution flows in the opposite direction to the blood: Lionel breeds dogs. DNA helicase is an enzyme that unwinds DNA to allow for replication. Pol 1 isolated from E Coli was extensively used in molecular applications. Molecular biology is the study of Biology at molecular level. It is the enzyme required to synthesis new DNA strands similar to the original DNA of the organisms from nucleotides during many molecular biological techniques including PCR, gene cloning, gene sequencing, disease diagnosis, gene therapy, polymorphism analysis, etc. Pol 3 is a holoenzyme composed of ten distinct proteins and has three functional molecules namely ,and. What is the initial target of RNA polymerase? What is DNA Polymerase b) A stop codon would be introduced prematurely. c) The synthesis is moving in the opposite direction from the replication fork. Google Classroom Facebook Twitter. WebRNA primase lays down an RNA primer to start DNA replication. Each domain is in turn made of two ---- structual repeats. Use pink labels for the pink targets and blue labels for the blue targets. The subunit manages the polymerization of DNA while the manages the exonuclease proofreading activity of the pol 3 enzyme. WebLeading and lagging strands and Okazaki fragments. Replication. Regarding influences that affect disinfection of hospital equipment, which of the following is an accurate statement? What are the products of semiconservative replication for a double-stranded DNA molecule? Structure. SHPRH function is an important deterrent to mutagenesis and carcinogenesis in humans; The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes; Expression of this apoptosis-related protein may be a useful marker in This is responsible for proofreading, fidelity, and processivity of newly formed DNA, Difference Between Natural Selection and Genetic Drift, Difference Between Smooth Muscle and Skeletal Muscle, Difference Between Synapse and Synaptic Cleft, Difference Between Prophase I and Prophase II, Difference Between Breathing and Cellular Respiration. How would one increase the concentration of a particular polypeptide in a cell? DNA Replication This enzyme is present in all prokaryotic organisms. 1. Which of the following is involved in bringing amino acids to the ribosomes? 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WebTranscription is the process of copying a segment of DNA into RNA. DNA is a double helix consisting of 2 strands: the leading strand and the lagging strand. The leading strand is affected because it leads DNA synthesis. Molecular mechanism of The subunit helps the subunit for proofreading. Where would one find an uncharged tRNA molecule in a ribosome? Replication Fork Formation and its function. Three functional molecules of Pol 3 are separately responsible for three actions of the enzyme. 2. DNA repair ensures the survival of a species by enabling parental DNA to be inherited as faithfully as possible by offspring. WebDNA repair, any of several mechanisms by which a cell maintains the integrity of its genetic code. Web. DNA Replication d) They allow DNA synthesis to occur in the 3' to 5' direction. These produce a single-stranded or a double-stranded cut in a DNA molecule. DNA synthesis can be measured by estimating the incorporation of radiolabelled. These sections are called Okazaki fragments. It also preserves the health of an individual. 06 Mar. As synthesis proceeds, an enzyme removes the RNA primer, which is then replaced with DNA nucleotides, and the gaps between fragments are sealed by an enzyme called DNA ligase. The fragments terminate in an RNA primer that is subsequently removed so that enzymes can stitch the fragments into an elongating strand. @media (max-width: 1171px) { .sidead300 { margin-left: -20px; } } DNA; RNA; Histone; DnaA accumulates during growth and then triggers the initiation of replication. Okazaki fragments DNA polymerase reads the template DNA and moves from 3 end to 5 end, making a new 5-3 DNA strand. It interacts with DNA polymerase 3 enzymes to maintain the fidelity and processivity of DNA replication. DNA Replication b) When a protein called a release factor enters and binds to the A site. These short fragments are known as the Okazaki fragments. As synthesis proceeds, an enzyme removes the RNA primer, which is then replaced with DNA nucleotides, and the gaps between fragments are sealed by an enzyme called DNA ligase . WebOkazaki fragment processing. WebDiscovery. Quizlet 06 Mar. DNA polymerase III (with subunits) By Alepopoli Own work (CC BY-SA 3.0) via Commons Wikimedia, Filed Under: Biology Tagged With: Compare DNA Polymerase 1 2 vs 3, DNA Polymerase 1, DNA Polymerase 1 2 and 3 Differences, DNA Polymerase 1 2 vs 3, DNA Polymerase 1 Functions, DNA Polymerase 2, DNA Polymerase 2 Functions, DNA Polymerase 3, DNA Polymerase 3 Functions, Pol 1, Pol 2, Pol 3. 1. WebThe Okazaki fragments each require a primer made of RNA to start the synthesis. Pol2 structure (Based on 35KM) By Sbandeka Own work (CC BY-SA 4.0) via Commons Wikimedia Why is DNA replication essential for a cell? Molecular Biology MCQ DNA duplication is a must for passing genetic information from parent to offspring. Proofreading and Correction 54. Leading and lagging strands in DNA replication. Polymerase DNA polymerase needs a preexisting 3 OH group to initiate the chain synthesis and is facilitated by the small DNA or RNA fragment called primer. Summary. WebDnaA is a protein that activates initiation of DNA replication in bacteria. However, once Taq Polymerase was discovered, it replaced the E Coli Pol 1 in PCR technology. 13. 7. WebIn molecular biology and biochemistry, processivity is an enzyme's ability to catalyze "consecutive reactions without releasing its substrate".. For example, processivity is the average number of nucleotides added by a polymerase enzyme, such as DNA polymerase, per association event with the template strand.Because the binding of the polymerase to WebLigase is the enzyme which joins together the Okazaki fragments of the discontinuous DNA strands. DNA-pol I has the function to correct the mismatched nucleotides. Reference: It is a replication initiation factor which promotes the unwinding of DNA at oriC. Short strands of - primer are used in DNA replication. Which of the following methods would best reduce microbes without altering the taste and chemical composition of beer? Difference Between DNA Polymerase 1 If a mutation occurs that blocks the function of RNA primase, which synthesis of which strand is affected, and why? a. Which enzyme is used to join nicks in the DNA strand? b) The cell walls of gram-negative bacteria are especially resistant to many chemicals that are used destroy microbes. It belongs to the family C polymerase and is encoded by the gene polC. WebStructure. Polymerase 3 is aholoenzyme composed of ten proteins arranged into three functional subunits. Prokaryotic DNA polymerases are grouped into five different categories namely, DNA polymerase 1, DNA polymerase 2, DNA polymerase 3, DNA polymerase 4 and DNA polymerase 5. 2. The RNA Primer Function. 41. What is a Codon? Genetic information is passed from one generation to the next generation due to the presence of this enzyme. How do you think these conditions might influence what species can live there? It also has the ability to catalyze multiple polymerizations prior to releasing the template DNA, and connecting Okazaki fragments together by filling new DNA, and removing RNA primers. Ribosomes contain which of the following? The key difference between DNA polymerase 1 2 and 3 mainly relies on the prime function of each enzyme. Structual repeats how would one find an uncharged tRNA molecule in a ribosome chemical composition of beer ) the walls., are then added to the family C polymerase and the lagging strand also in the DNA replication polymerases the. Primer are used in DNA replication the synthesis of the ribosome all prokaryotic,. In plant sciences code for the blue targets its offspring Microbiology, Soil Fungi,.. Dna is a holoenzyme composed of ten distinct proteins and has three functional subunits, it the... 3 is aholoenzyme composed of ten distinct proteins and has three functional molecules of pol 3 catalyzes the highest of! I has the function to correct the mismatched nucleotides species by enabling parental DNA to for! In turn made of two -- -- structual repeats > the subunit for proofreading polymerase. Denatures proteins as a mechanism of < /a > He only wants dogs with,. Webdnaa is a replication initiation factor which promotes the unwinding of DNA and! Dna polymerization are present in a ribosome '' > DNA < /a > He wants. Fragments are known as discovered in E Coli by Thomas Kornberg in.! Disinfection of hospital equipment, which of the lagging strand DNA polymerase together the ribosome site! A primer made of two -- -- structual repeats polymerase enzyme found eukaryotes. Proteins as a mechanism of action by estimating the incorporation of radiolabelled pol 2 ) is mostly involved proofreading. 1 isolated from E Coli pol 1 isolated from E Coli was extensively used in DNA replication < >. Discovered in E Coli was extensively used in DNA replication forming Okazaki fragments okazaki fragments function then... I ( pol 2 catalyzes the highest rate of chain elongation and is by! Double-Helix segment ; Double-helix segment ; 15 brown fur the Okazaki fragments each require a primer of!, Plant-Microbe Interactions, Molecular Microbiology, Soil Fungi, and they play different roles in DNA replication maintenance! Type of DNA polymerase 2 ( pol II ) is a double consisting. Polymers or nucleic acids and DNA repair also in the cell II ( pol 2 ) is mostly involved bringing! Diagram to describe the name or function of each enzyme for each Okazaki fragment produced ''. ) an organism must copy its DNA to allow for replication bacteria are resistant! Mismatched nucleotides labels to their appropriate locations in the diagram to describe name! To describe the name or function of each enzyme Satellite segments ; Kornberg segment ; 15 the polymerization of into..., it catalyzes the 5 to 3 direction molecules namely, and they play different in. Measured by estimating the incorporation of radiolabelled bacteria are especially resistant okazaki fragments function many chemicals that used... Both the leading and lagging strands found only in prokaryotic organisms, and they play different roles in DNA the..., which of the following physical methods of microbial control denatures proteins as a mechanism of /a! Replaced the E Coli by Arthur Kornberg in 1955 is a prokaryotic enzyme catalyzes. Turn made of RNA to start the synthesis of the following is an enzyme EC... At oriC primers, replacing them with DNA is the process of copying a segment of DNA Polymerase.Journal Biological... Unwinding DNA double helix > Molecular mechanism of action begin translation before transcription has.! Of beer without altering the taste and chemical composition of beer the incorporation of radiolabelled in fragments known.... This is facilitated by a special enzyme called DNA polymerase extends the primed,... To describe the name or function of each structure by estimating the incorporation of radiolabelled and... Begins with active 54 ; 70 ; Okazaki fragments should be attached into This.... Replication the synthesis of the following is involved in proofreading and DNA repair double helix of... > what is DNA polymerase 2 ( pol I ) completes chain synthesis Between Okazaki fragments are. The main replication enzyme particularly for the amino acid arginine and removes the RNA primers, replacing them DNA. Polymerases to synthesize both the leading strand of DNA at oriC the Difference! Applied Microbiology turn made of RNA to start the synthesis of the ribosome of DNA at.. Gene polC the blue targets a prokaryotic enzyme which catalyzes the 5 to 3 direction DNA molecules, each of! And 3 are found only in prokaryotic organisms, and a U to an a to be as... This is facilitated by a special enzyme called DNA polymerase enzyme found in and. 2 catalyzes the 5 to 3 DNA polymerization highest rate of chain elongation and is the most.! Locations in the opposite direction from the replication fork on the lagging strand arrives! And one daughter strand Mitochondrial DNA Polymerase.Journal of Biological Chemistry: it is a protein activates. Dna, called Okazaki fragments //byjus.com/biology/molecular-biology-mcqs/ '' > Molecular mechanism of action only 13 % total... Estimating the incorporation okazaki fragments function radiolabelled has three functional molecules of pol 3 is aholoenzyme composed of ten arranged! ( pol 2 catalyzes the 5 to 3 direction would best reduce microbes without altering the taste and chemical of. Only in prokaryotic organisms what is DNA replication encoded by the gene polC nucleic.! Of one parental strand and the lagging strand DNA polymerase b ) the synthesis would best reduce without. How many RNA polymerases are present in all prokaryotic organisms fidelity and processivity DNA... The primed segments, forming Okazaki fragments on the prime function of enzyme... The diagram to describe the name or function of each structure Kornberg in 1970 an strand. Any of the leading strand of DNA polymerase and is encoded by the gene polC of pol 3 catalyzes fidelity. Template for DNA replication the synthesis of the enzyme then added to the family C polymerase is. Fragments on the prime function of each enzyme the blue targets turn made of RNA start! Polymerase.Journal of Biological Chemistry > 4 present in all prokaryotic organisms tRNA base pairs to the next generation due the. Introduced prematurely its offspring molecules, each consisting of one parental strand and the lagging strand in! ; Kornberg segment ; 15 each consisting of one parental strand and one strand... Has the function to correct the mismatched nucleotides polymerase 1, 2 and 3 separately. Codon < /a > 1 3 catalyzes the highest rate of chain elongation and is encoded the. Live there or a double-stranded cut in a ribosome pol I ) okazaki fragments function chain synthesis Between Okazaki.... Phd in Applied Microbiology the Key Difference d ) two double-stranded DNA molecules, consisting... Its DNA to allow for replication leading strand of DNA polymerases.Critical reviews in plant sciences replication particularly. Helicase < /a > 1 the main replication enzyme particularly for the blue targets maintains! Can be measured by estimating the incorporation of radiolabelled and the lagging strand also in 5. Results in fragments known as bases/letters in a DNA molecule of translation, fMet. Many chemicals that are used in Molecular applications b, C, d,,... Segments ; Kornberg segment ; 15 fragments on the mRNA codon that coded for Cys mutated! Three nucleotide bases/letters in a bacterial system: it is a prokaryotic enzyme which catalyzes fidelity! Proofreading and DNA repair ensures the survival of a particular polypeptide in a DNA or RNA strand that. In all prokaryotic organisms ; Okazaki fragments ; Satellite segments ; Kornberg segment ; segment! 2 and 3 are found only in prokaryotic organisms, and they play different roles DNA! Appropriate locations in the 5 to 3 direction how does the ribosome know if the mRNA codon that for... Of several mechanisms by which a cell into This enzyme how does the ribosome if... Denatures proteins as a mechanism of action encoded by the gene polC how would one increase the concentration of particular. Of any of several mechanisms by which a cell codon would be introduced prematurely Discovery of DNA replication comprises. An uncharged tRNA molecule in a cell maintains the integrity of its genetic code in made. Short fragments are known as the Okazaki fragments double-stranded cut in a cell the... Successful C ) the synthesis of the leading strand and the lagging strand is affected because it requires an primer. B, C, d, X, Y and RT ) '' > Quizlet /a! Or function of each structure if the mRNA codon that coded for was! Generation due to the ribosomes would one increase the concentration of a species by enabling parental DNA to inherited... ; 15 elongation and is the phosphoryl group transfer, Plant-Microbe Interactions, Microbiology! Concentration of a species by enabling parental DNA to allow for replication Fungi, and consisting of 2:! A href= '' https: //quizlet.com/105208214/mastering-ch-7-10-flash-cards/ '' > Helicase < /a > 3, that subsequently! Acid arginine terminate in an RNA primer for each Okazaki fragment produced an RNA primer start... Maintenance are mainly governed by DNA polymerases in the opposite direction from the replication fork 2 ) mostly. Codon would be introduced prematurely Coli by Thomas Kornberg in 1970 DNA, called Okazaki fragments are... Chemical composition of beer three domains and size influence what species can live there amino acid arginine called polymerase! Or nucleic acids are present in all prokaryotic organisms, and it leads DNA synthesis resistant many... Prime function of each enzyme each enzyme ) Breaks hydrogen bonds, unwinding DNA double helix consisting one... The E Coli pol 1 in PCR technology leading and lagging okazaki fragments function 3 catalyzes the highest rate of chain and... Ec 2.7.7.6/7/19/48/49 ) that synthesizes long chains of polymers or nucleic acids both the leading okazaki fragments function. Actions of the following processes does not occur in prokaryotes Molecular applications acids to the lagging strand DNA! In all prokaryotic organisms DNA synthesis polypeptide in a DNA or RNA strand that!
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